The global transfer of disease in the pre-modern world helped in
the colonization of the Americas because the native American
Indians were not immune to the diseases that the settlers and
colonizers brought with them. The Europeans were more or less
immune to small pox, but the native Americans, having been cut
off from the rest of the world for millions of years, had no
defence against it. These germs killed and wiped out whole
communities, paving the way for foreign domination. Weapons
and soldiers could be destroyed or captured, but diseases could
not be fought against.
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